Welcome to Mesilla Valley Pharmacy

Welcome to Las Cruces, home to America’s most innovative community pharmacy! Mesilla Valley Pharmacy is proud to feature our historic downtown location in your community. Our dedicated team is committed to delivering unparalleled service and care, ensuring that every person who visits us experiences a higher level of pharmacy service with convenience at its core.

Voted Las Cruces’s Best Pharmacy 2023

Our Services

Med Sync

The CDC prevention estimate found that 50% of patients don’t take their medications as prescribed. We can fix that.


Don’t worry about driving to pickup your refills, same day delivery available. Prescription mail offered for NM & TX.

Personalized Packaging

Our single and multi-dose  packaging makes it easier to accurately administer and chart medications.

Long-term care

 We streamline drug ordering, administration, and disposal procedures, so you can focus on your patients.

Clinical Services

Our pharmacists work at the top of their license, which allows them to prescribe birth control, HIV PEP, & tobacco cessation medications.

In-store Shopping

Sick of harsh fillers like PEGs? Our Good Neighbor Pharmacy vitamins are perfect for anyone looking to improve their wellness.


Easily stay up to date on all your vaccinations. Save some time and register online. Curbside and home appointments available.


We specialize in preparing individualized solutions when no commercial alternatives are available. Non-sterile preparations.

The best prescription experience in Las Cruces.

Welcome to Mesilla Valley Pharmacy! We are proud to deliver first-class healthcare right in your backyard. Our Downtown Dispensary opening is a historic moment for Las Cruces and America – we stand as the nation’s very first Cannabis Pharmacy! Experience convenience, expertise, and unparalleled care today with us. At our pharmacy, getting quality medicine has never been easier or more enjoyable. The wait times here are shorter than other pharmacies because our pharmacists take pride in providing personalized service – they get know you on an individual level so that together you can strive towards optimal health outcomes at all times

Located in the Heart of Downtown Las Cruces

Visit our Neighbors, Support Local Business.